Small-Angle X-Ray Scattering Study of Carbosilane Dendrimers in Hexane Solution
- Dr. Eleonora SHTYKOVA
- Dr. Eleonora SHTYKOVA (1. IC RAS, Moscow, Russia, 2. MSU, Moscow, Russia)
- Prof. L.A. FEIGIN (IC RAS)
- Dr. V.V. VOLKOV (IC RAS, Moscow, Russia)
- Dr. Yu.N. MALAKHOVA (1.MTU, IFCT, Moscow, Russia; 2.NRC «Kurchatov Institute», Moscow, Russia)
- Dr. D.R. STRELTSOV (1. NRC «Kurchatov Institute», Moscow, Russia; 2. ISPM RAS, Moscow, Russia)
- Dr. A.I. BUZIN (ISPM RAS, Moscow, Russia)
- Prof. S.N. CHVALUN (1.NRC “Kurchatov Institute, Moscow, Russia; 2. ISPM RAS, Moscow, Russia)
- Prof. A.M. MUZAFAROV (1. INEOS RAS Moscow, Russia; 2. ISPM RAS, Moscow, Russia)
Dendrimers are three-dimensional, highly branched, monodisperse macromolecules with a well-defined regular structure. They possess unique properties due to its size, composition and controlled functionalization. Among the variety of dendrimers, carbosilane dendrimeric macromolecules attracted great attention for their reactive functional groups, chemical inertness of the molecular skeleton and possibility of medical and biological applications [1, 2]. In the present work three-dimensional structure of monodisperse carbosilane dendrimers of zero, third and sixth generations were studied by small-angle X-ray scattering (SAXS) in hexane solution. Using modern methods of SAXS data interpretation, including procedure of ab initio modeling, spherical shape and internal architecture of the dendrimers were revealed depending on the generation number and on the number of cyclosiloxane end groups constituting a shell of the macromolecules. With the help of a computer simulation a possibility of shape reconstruction of the dendrimer molecules in clusters has been considered, and the analysis of the intermolecular interaction of the dendrimers in solution was performed applying the latest developments of the method of molecular tectonics.
This work was supported in part by Russian Foundation for Basic Researches (projects 16-03-00379 and 16-03-00375) References  Dendrimers and other dendritic polymers / Ed. by J.M. Frechet, D.A. Tomalia. - N.Y.: Wiley & Sons, 2001.  Kim Y.H., Webster O.W., J. Am. Chem. Soc., 1990, 112, 4592.