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SUMMARY:Investigation of the possibility for medical radioisotopes product
 ion on linear proton accelerator I-2
DTSTART;VALUE=DATE-TIME:20230914T031000Z
DTEND;VALUE=DATE-TIME:20230914T033000Z
DTSTAMP;VALUE=DATE-TIME:20260513T214739Z
UID:indico-contribution-2601@indico.inp.nsk.su
DESCRIPTION:Speakers: Nick Markov (NRC "Kurchatov Institute" (ITEP))\nToda
 y\, heavy particle accelerators are increasingly used in medicine\, as in 
 terms of developing and improving of the external beam therapy (proton and
  ion beam therapy)\, as well as  in terms of introducing new methods of nu
 clear medicine (production of therapeutic and diagnostic radioisotopes). I
 f talking about the usage of accelerators in nuclear medicine\, here\, in 
 addition to low-energy accelerators (up to 20 MeV) used for PET radioisoto
 pes production (F-18\, N-13\, C-11)\, accelerators of the medium (20 - 35 
 MeV) and high energies (more than 35 MeV) ranges are of increasing interes
 t. This is primarily due to the growing demand for radioisotope products\,
  the decommissioning of many nuclear reactors used to produce medical radi
 oisotopes\, as well as the development of  new methods in nuclear medicine
 \, such as in theranostics and corresponding requirements for the new prom
 ising radioisotopes for diagnostics and therapy.\nAt the same time\, from 
 the point of view of accelerator technologies\, the most common types of a
 ccelerators used to produce radioisotopes are cyclotrons. However\, projec
 ts aimed for the development of dedicated linear accelerators for radioiso
 tope production\, regularly appear in many countries of the world. Among t
 he advantages of this approach\, one can note the possibility to obtain a 
 facility equipped with exit channels with various beam energies (thereby e
 xpanding the list of produced isotopes)\, among the disadvantages\, one ca
 n note the lower values of the average beam current (as a result\, the pos
 sibility of obtaining lower activities)\, as well as the large dimensions 
 of the linear accelerator. As a result\, today the market is dominated by 
 cyclotrons\, while the linear accelerators used to produce radioisotopes a
 re research facilities.\nAt present\, the Kurchatov Complex for Theoretica
 l and Experimental Physics (ITEP) successfully operates the I-2 linear pro
 ton accelerator\, which was previously used as an injector of the U-10 syn
 chrotron. The main area of application is related to research in the field
  of the radiation damages of the electronic components\, as well as to the
  technological irradiation of elements of power semiconductor electronics.
  In addition\, researches in the field of radiobiology and accelerator tec
 hnology are carried out. In accordance with the design parameters (proton 
 energy in the output channel 24.5 MeV\, average beam current 2.5 μA)\, th
 e accelerator can also be used to produce various types of radioisotopes. 
 As part of the development of this area\, in collaboration with specialist
 s from the Kurchatov Complex of Physical and Chemical Technologies\, resea
 rch project was started to investigate the possibility of obtaining clinic
 ally significant activities of the I-123\, used in SPECT\, at the I-2 acce
 lerator. In this paper the results of the first experimental measurements 
 of the main beam parameters\, irradiation a gaseous Xe-124 target and foll
 owing extraction of the I-123 radioisotope are presented. Based on these r
 esults\, further steps for the modernization of the accelerator systems\, 
 as well as the design of the new target\, in order to ensure the possibili
 ty of obtaining I-123 activities at the level of several GBq were develope
 d.\n\nhttps://indico.inp.nsk.su/event/114/contributions/2601/
LOCATION:Budker INP room 500
URL:https://indico.inp.nsk.su/event/114/contributions/2601/
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