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Contribution

X-ray structural analysis

SR XRD Phase Analysis of Kidney Stones within Model Object at VEPP-4M Storage Ring

Speakers

  • Mr. Alexandr NIZOVSKII

Primary authors

Co-authors

Content

The results of the study of kidney stones of different mineral composition are presented. Previously, studies were conducted of human kidney stones obtained from patients, both after lithotripsy and after abdominal operations [1]. The experiments mentioned above were carried out at beamline No.4 of VEPP-3 storage ring at Siberian Synchrotron and Terahertz Radiation Center (SSTRC), Novosibirsk, Russia, using photon energy E=33.7 keV. Diffraction patterns were registered by Image Plate area detector MAR345, the thickness of model sample was ~20 cm, exposure time 2 min. Definite limitations on object thickness as well as exposure time appear to be crucial for this photon energy. It is clear that to decrease radiation loading and to remove limitation on the sample size (patient weight) the higher radiation energy is to be used. The experiments described here were executed at beamline No.8 of VEPP-4M storage ring at SSTRC. The electron energy of this storage ring is 4.5 GeV and the radiation is emitted by 11-pole wiggler. Such source provides essential photon flux at photon energy about 100 keV, which is well suitable for In Vivo kidney stones diagnostics. 2D XRD pattern of kidney stones of different phase composition were registered by Toshiba FDX4343R Flat Panel detector. The 1D pattern can be obtained from 2D pattern by integration of diffracted intensity over azimuthal angle. 1D XRD patterns of free kidney stone and stone in model object which was cylindrical plastic vessel of 17 cm diameter filled with water were recorded and discussed.

  1. Ancharov A.I., Potapov S.S., Moiseenko T.N., Feofilov I.V., Nizovskii A.I.. Model Experiment of in vivo Synchrotron X-Ray Diffraction of Human Kidney Stones. Nuclear Instruments and Methods in Physics Research Section A. 2007. V. 575. N 1-2. P. 221-224.