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SUMMARY:Influence of terahertz laser irradiation on the morphology of chic
 ken hepatocytes
DTSTART;VALUE=DATE-TIME:20160705T090000Z
DTEND;VALUE=DATE-TIME:20160705T100000Z
DTSTAMP;VALUE=DATE-TIME:20260722T173659Z
UID:indico-contribution-1232@indico.inp.nsk.su
DESCRIPTION:Speakers: Eugeny Zelentsov (MC "Integral medicine")\nPreviousl
 y\, we have discovered the erythrocyte membrane disruption in aqueous solu
 tion under the influence of high-power pulses of the Novosibirsk free elec
 tron laser operated at the wavelength of 120-170 microns\, with the averag
 e power density of 10W/cm2. This fact was explained by the emergence of po
 werful ultrasound caused by water absorption of terahertz radiation. In th
 is report hepatocytes were studied under the same conditions. The aim of t
 he study was to evaluate the effects of radiation on normal hepatocytes in
  comparing with previous studies of red blood cells.\nLiver fragments were
  sampled and transferred into 500ul of aqueous suspension and irradiated w
 ith non-focused beam at different exposure time. Samples were examined his
 tologically using the atomic force microscopy (tapping mode) in the native
  form. Exposure of 2-4 seconds resulted in single membrane injuries and a 
 slight change in the shape of hepatocytes. Exposure of 5- 10 seconds or mo
 re leads to significant damage of hepatocyte membranes.\nResults have full
 y confirmed the earlier experiments. Destructive effects of high-power THz
  pulses on biological objects in the aquatic environment were proven.\n\nh
 ttps://indico.inp.nsk.su/event/3/contributions/1232/
LOCATION:Budker INP 2nd and 3rd floors
URL:https://indico.inp.nsk.su/event/3/contributions/1232/
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