Speaker
Description
Unique properties of X-ray fluorescent analysis with synchrotron radiation and classical morphological method allowed to reveal interrelation between the trace elements content and structure of lymph nodes. Belonging of lymph nodes to different regions is defining in formation of a certain microelemental profile and features of the microanatomic organization of lymph nodes. Lymph nodes have different functional specialization with prevalence of immune or drainage function and a certain microelemental composition. The inguinal lymph node has active drainage function because of the developed sinus system at the maximum of Mn, Fe, Zn concentration; immune function prevails in a tracheobronchial lymph node at the low content of all trace elements; the mesenteric lymph node has evenly developed drainage and immune functions at the maximum of Cu, Se contents. The content of trace elements is considered as the leading mechanism limitation the structural organization of lymph nodes. Innovative approach helped to reveal formation of lymphoid-microelemental association. Features of this association modify the structural organization of lymph nodes depending on localization (region specifics).
Summary
Microelemental limitation of lymph nodes structure according to the X-ray fluorescent analysis with a synchrotron radiation
O.V. Gorchakova1, Yu.P. Kolmogorov1, V.N. Gorchakov1,2*, G.A. Demchenko3, S.N. Abdreshov3
1Research Institute of a clinical and experimental Lymphology – branch of Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Science, Novosibirsk, Russia
2Novosibirsk State University, Novosibirsk, Russia
3Institute of Physiology of Human and Animals of Committee of Science of the Ministry of Education and Science of the Republic of Kazakhstan, Almaty, Kazakhstan
